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Mary Beckerle

Dist Prof of Biology, CEO & Director, Huntsman Cancer Institute
*Main Appointment Outside SBS*

Ph.D. University of Colorado, Boulder


Office/Building: HCI
Phone: 801-581-4485
Email: mary.beckerle@hci.utah.edu
Beckerle Lab: https://uofuhealth.utah.edu/huntsman/labs/beckerle/

Research Statement


Dr. Beckerle's principal appointment is outside the School of Biological Sciences. Please contact the Beckerle lab directly.

Research Interests


General Interests
Specific Interests
  • Cell adhesion and motility

Selected Publications


  • Mechanical stress triggers nuclear remodeling and the formation of Transmembrane Actin Nuclear lines with associated Nuclear Pore Complexes. Hoffman LM, Smith MA, Jensen CC, Yoshigi M, Blankman E, Ullman K, Beckerle MC. (2020). Mol Biol Cell. 2020 Jan 22:mbcE19010027
  • Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response. Pishas KI, Drenberg CD, Taslim C, Theisen ER, Johnson KM, Saund RS, Pop IL, Crompton BD, Lawlor ER, Tirode F, Mora J, Delattre O, Beckerle MC, Callen DF, Sharma S, Lessnick SL. Mol Cancer Ther. 2018 Sep;17(9):1902-1916. doi: 10.1158/1535-7163.MCT-18-0373. Epub 2018 Jul 11.
  • Mechanical signals activate p38 MPAK pathway-dependent reinforcement of actin via mechanosensitive HspB1. Hoffman L, Jensen CJ, Yoshigi M, Beckerle MC (2017) Mol Biol Cell e17020087
  • The actin regulator zyxin reinforces airway smooth muscle and accumlates in airways of fatal asthmatics. Rosner SR, Pascoe CD, Blankman E, Jensen CJ, Krishnan R, James AL, Elliot JG, Green FH, Liu JC, Seow CY, Park J, Beckerle MC, Pare PD, Fredberg JJ, Smith MA (2017) PLOS One e0171728