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Research |
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| The Jorgensen laboratory studies the molecular basis of synaptic transmission, focusing on the mechanisms of synaptic vesicle fusion and synaptic strength. Other research projects include studies of neuroendocrine secretion, specifically, the modulaton of behavioral states caused by changes in the environment, such as the presence of food or mates. Another goal is to understand the neuronal circuits that give rise to behaviors, particularly the generation of rhythmic behavior. Other research groups in the laboratory are studying transposons in the worm, as well as double-strand break repair of DNA. | ||
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C. elegans - All of our Projects involve the use of this nematode as a model organism |
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GABA - The molecular mechanisms required for the neurotransmitter GABA | |
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Synaptic vesicle exocytosis - Molecules involved in synapse function | |
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Biological clock - A one minute behavioral clock in C. elegans uses the IP3 receptor, calcium waves and a novel transmitter. | |
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Sexual attraction - The neural basis for gender-specific behaviors. | |
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Transposons and DNA - Fly transposons can be mobilized in worms to generate double strand breaks. | |
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Superresolution Microscopy - Developing and building microscopes that break the Abbe limit. | |