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Publications |
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| Sato K., Ernstrom G.G., Watanabe S., Weimer R.M., Chen C.H., Sato M., Siddiqui A., Jorgensen E.M., Grant B.D. 2009. Differential requirements for clathrin in receptor-mediated endocytosis and maintenance of synaptic vesicle pools. Proc Natl Acad Sci USA 106:1139-1144.. | ||
| Gu, M., K. Schuske, S.i Watanabe, Q. Liu, P. Baum, G. Garriga, and E.M. Jorgensen. 2008. mu2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans. J. Cell Biol. 183, 881-892. | ||
Frøkjær-Jensen, C., M.W. Davis, C.E. Hopkins, B. Newmann, J.M. Thummel, S-P. Olesen, M. Grunnet and E.M. Jorgensen. 2008. Single copy insertion of transgenes in C. elegans. Nature Genetics 40, 1375-1383. |
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| Hammarlund, M., P. Nix, L. Hauth, E.M. Jorgensen, and M..J. Bastiani. 2009. Axon regeneration requires a conserved MAP kinase pathway. Science 323, 802-806. | ||
Palfreyman, M., and E.M. Jorgensen. 2009. In vivo analysis of membrane fusion. In Encyclopedia of Life Sciences, John Wiley & Sons. Chichester http://www.els.net/ [DOI: 10.1002/ 9780470015902.a0020891]. Review. |
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| Palfreyman, M., and E.M. Jorgensen. 2008. Roles of SNARE proteins in synaptic vesicle fusion. In Molecular Mechanisms of Neurotransmitter Release, Humana Press, p35-59. Review | ||
| Davis, M.W., J. Morton, D. Carroll and E.M. Jorgensen. 2008. Gene activation using FLP recombinase in C. elegans. PLoS Genetics 4(3) e1000028. | ||
| Robert, V.J., M.W. Davis, E.M. Jorgensen and J-L Bessereau. Gene conversion and end-joining repair double-strand breaks in the C. elegans germline. Genetics 180, 673 - 679. | ||
| Hammarlund, M., S. Watanabe, K. Schuske, and E.M. Jorgensen. 2008. CAPS and syntaxin dock dense core vesicles to the plasma membrane in neurons. Journal of Cell Biology 180 483-491. | ||
Pan, C.L, P. Baum, M. Gu, E. M. Jorgensen, S. Clark, and G. Garriga. 2008. C. elegans AP-2 and retromer control Wnt secretion by regulating MIG-14/Wntless. Developmental Cell 14, 132-139. |
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Jung, N., M. Wienisch, M. Gu, J.B. Rand, S. L Müller, G. Krause, E. M. Jorgensen, J. Klingauf, V. Haucke. 2007. Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2. Journal of Cell Biology 179, 1497-1510. |
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Beg, A., P., G. Ernstrom, P. Nix, M.W. Davis and E.M. Jorgensen. 2008. Protons act as a transmitter for muscle contraction in C. elegans. Cell 132: 149-160. |
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Williams, S.L., S. Lutz, N.K. Charlie, C. Vettel, M. Ailion, C.Coco, J.J.G. Tesmer, E.M. Jorgensen, T. Wieland, and K.G. Miller. 2007. Trio's Rho-specific GEF domain is the missing Gq effector in C. elegans. Genes and Development 21, 2731-2746. |
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White, J.Q., T.J. Nicholas, J. Gritton, L. Truong, E.R. Davidson and E.M. Jorgensen. 2007. The sensory circuitry for sexual attraction in C. elegans males. Current Biology 17, 1847-1857. |
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Peters, M. T. Teramoto, J.Q. White, K. Iwasaki and E. M. Jorgensen. A calcium wave mediated by gap junctions coordinates a rhythmic behavior in C. elegans. 2007. Current Biology 17, 1601-1608. |
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Jospin, M., S. Watanabe, D. Joshi, S. Young, K. Hamming, C. Thacker, T. Snutch, E.M. Jorgensen and K. Schuske. 2007. UNC-80 and the NCA ion channels contribute to endocytosis defects in synaptojanin mutants. Current Biology 17, 1595-1600. |
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Hammarlund, M., M. Palfreyman, S. Watanabe, S. Olsen, and E.M. Jorgensen. 2007. Open syntaxin docks synaptic vesicles. PLoS Biology 5 (8): e198, 1695-1711. |
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Schuske, K. M.T. Palfreyman, S. Watanabe, and E. M. Jorgensen. 2007. UNC-46, a novel protein required for trafficking of the vesicular GABA transporter. Nature Neuroscience 10, 846-853. |
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Palfreyman, M., and E.M. Jorgensen. 2007. PKC defends crown against Munc13. Neuron 54, 179-180. Review. |
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Speese, S., M. Petrie, K. Schuske, M. Ailion, K. Ann, K. Iwasaki, E.M. Jorgensen, and T.F.J. Martin. 2007. UNC-31 (CAPS) Is Required for Dense-Core Vesicle But Not Synaptic Vesicle Exocytosis in Caenorhabditis elegans. Journal of Neuroscience 27, 6150-6162. |
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Bednarek, E., L. Schaheen, J. Gaubatz, E.M. Jorgensen and H. Fares. 2007. The plasma membrane calcium-ATPase is required for clathrin-mediated endocytosis. Traffic 8, 543-553. |
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Hammarlund, M., E.M. Jorgensen, M.J. Bastiani. 2007. Axons break in animals lacking beta-spectrin. J Cell Biol. 176, 269-275. |
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Morton, J., M.W. Davis, E.M. Jorgensen, and D. Carroll. 2006. Induction and repair of zinc-finger nuclease-targeted double-strand breaks in C. elegans somatic cells. Proc Natl Acad Sci USA 103, 16370-16375. |
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Abraham, C., H. Hutter, M.T. Palfreyman, G. Spatkowski, R. Weimer, R. Windoffer, E.M. Jorgensen and R. Leube. 2006. Synaptic tetraspan vesicle membrane proteins are conserved but not needed for synaptogenesis and neuronal function in C. elegans. Proc Natl Acad Sci USA 103, 8227-8232. |
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Wardell, B., P.S. Marik, D. Piper, T. Rutar, E.M. Jorgensen and B.A. Bamber. 2006. Residues in the first transmembrane domain of the Caenorhabditis elegans GABAA receptor confer sensitivity to the neurosteroid pregnenolone sulfate. Brit. J. Pharm. 148, 162-172. |
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Davis*, M.W., M. Hammarlund*, T. Harrach, S. Olsen, and E.M. Jorgensen. 2005. Rapid single nucleotide polymorphism mapping in C. elegans. BMC genomics 6, 118. |
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Jorgensen, E.M. 2005. GABA. WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.14.1, http://www.wormbook.org. Book Chapter. |
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Hammarlund, M.*, M.W. Davis*, H. Nguyen, D. Dayton, and E.M. Jorgensen. 2005. Heterozygous insertions alter crossover distribution but allow crossover interference in C. elegans. Genetics, 171: 1047-1056. |
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Williams, D.C., T. Boulin, A.F. Ruaud, E.M. Jorgensen, and J.L Bessereau. 2005. Characterization of Mos1-Mediated Mutagenesis in Caenorhabditis elegans: A Method for the Rapid Identification of Mutated Genes. Genetics, 169: 1779-1785. |
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Bamber, B.A., J.E. Richmond, J.F. Otto and E.M. Jorgensen. 2005. The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction. Br. J. Pharm. 144, 502 - 509. |
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Davis, M.W., A.J. Birnie, A.C. Chan, A.P. Page, and E.M. Jorgensen. 2004. A conserved metalloprotease mediates ecdysis in C. elegans. Development 131, 6001-6008. |
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Jorgensen, E.M. 2004. Dopamine: should I stay or should I go now? Nature Neuroscience 7, 1019-1021. Review. |
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Schuske, K., and E.M. Jorgensen, 2004. The vesicular glutamate transporter: shooting blanks. Science 304, 1750-1752. Review. |
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Schuske, K., A. Beg, and E.M. Jorgensen, 2004. The GABA nervous system in Caenorhabditis elegans. Trends in Neurosci. 27, p407-414. Review. |
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Rostaing, P., R.M. Weimer, E.M. Jorgensen, A. Triller and J.L Bessereau. 2004. Preservation of immunoreactivity and fine structure of C. elegans tissues using high-pressure freezing. J. Histochemistry and Cytochemistry 52: 1–12. |
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Schuske, K.R., J.E. Richmond, D.S. Matthies, W.S. Davis, S. Runz, D.A. Rube, A.M. van der Bliek and E.M. Jorgensen. 2003. Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin. Neuron 40, 749-762. |
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Beg, A., and E.M. Jorgensen. 2003. An excitatory GABA receptor. Nature Neuroscience 6, 1145-1152. |
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Lesa, G., M. Palfreyman, D. H. Hall, M. T. Clandinin, C. Rudolph, E.M. Jorgensen and G. Schiavo. 2003. Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. J. Cell Science 116, 4965-4975. |
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Weimer, R., J.E. Richmond, W.S. Davis, J. Gritton, G. Hadwiger, M. Nonet and E.M. Jorgensen. 2003. Defects in synaptic vesicle docking in unc-18 mutants. Nature Neuroscience 6, 1023-1030. |
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Weimer, R., and E.M. Jorgensen. 2003. Controversies in synaptic vesicle exocytosis. J. Cell Sci. 116, 3661-3666. Review. |
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Bamber, B.A.; R.E. Twyman, and E.M. Jorgensen. 2003. Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans British Journal Pharmacology, 138, 883-893. |
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Corsi A.K. T.M., Brodigan, E.M. Jorgensen, M. Krause. 2002. Characterization of a dominant negative C. elegans Twist mutant protein with implications for human Saethre-Chotzen syndrome. Development 129: 2761-2772. |
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Jorgensen, E.M., and S.E. Mango. 2002. The art and design of genetic screens: Caenorhabditis elegans. Nature Review Genetics 3, 356-369. |
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Halevi, S., J. McKay, M. Palfreyman, L. Yassin, M. Eshel, E. Jorgensen, and M. Treinin. 2002. The C. elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors. EMBO J. 21, 1012-1020. |
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Knobel, K., W. Davis and E.M. Jorgensen, and M. Bastiani. 2001. UNC-119 suppresses axon branching in C. elegans Development 128: 4079-4092. |
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Koushika, S., J. E. Richmond, G. Hadwiger, R. Weimer, E. M. Jorgensen and M. L. Nonet. 2001. A post-docking role for active zone protein Rim. Nature Neuroscience 4, 997-1005. |
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Bessereau, J.L., A. Wright, D.C. Williams, K. Schuske, M.W. Davis and E.M. Jorgensen. 2001. Mobilization of a Drosophila transposon in the Caenorhabditis elegans germ line. Nature 413, 70-74. |
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Harris, T.W., K. Schuske, and E.M. Jorgensen. 2001. Synaptic vesicle endocytosis in C. elegans. Traffic 2, 597-605. Review. |
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Richmond, J.E., R.M. Weimer, and E.M. Jorgensen. 2001. An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming. Nature 412, 338-341. |
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Yook, K.J., S.R. Proulx and E.M. Jorgensen. 2001. Rules of nonallelic noncomplementation at the synapse in Caenorhabditis elegans. Genetics 158, 209-220. |
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Harris, T.W., E. Hartwieg, H.R. Horvitz, and E.M. Jorgensen. 2000. Mutations in synaptojanin disrupt vesicle recycling. J Cell Biol 150, 589-600. |
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Hammarlund, M., W.S. Davis and E.M. Jorgensen. 2000. Mutations in b-spectrin disrupt axon outgrowth and sarcomere structure. J. Cell Biol. 149, 931-942. |
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Richmond, J.E., W.S. Davis, and E.M. Jorgensen. 1999. UNC-13 is required for synaptic vesicle fusion in C. elegans. Nature Neuroscience 2, 959-964. |
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Dal Santo, P., M.A. Logan, A.D. Chisholm and E.M. Jorgensen. 1999.The inositol trisphosphate receptor regulates a 50 second behavioral rhythm in C. elegans. Cell 98, 757-767. |
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Knobel, K., E.M. Jorgensen and M. Bastiani. 1999. Growth cones stall and collapse during C. elegans development. Development 126, 4489-4498. |
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Richmond, J.E., and E.M. Jorgensen. 1999. One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction. Nature Neuroscience 2, 791-797. |
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Nonet, M., A.M. Holgado, F. Brewer, C.J. Serpe, B.A. Norbeck, J. Holleran, L. Wei, E. Hartweig, E.M. Jorgensen, and A. Alfonso. 1999. UNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesicles. Mol. Biol. Cell 10, 2343-2360. |
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Bamber, B., Beg, A., Twyman, R. and E.M. Jorgensen. 1999. The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor J. Neuroscience 19, 5348-5359. |
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Jin, Y., Jorgensen, E., Hartwieg, E. and H.R. Horvitz. 1999. The C. elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development. J. Neuroscience 19, 539-548. |
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Chalfie, M., Jorgensen, E.M.. 1998. C. elegans neuroscience: Genetics to genome. Trends Genet. 14:506-512. |
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Gilbert, S.F., and E.M. Jorgensen. 1998. Wormwholes: a commentary on K.F. Schaffner's 'Genes, behavior and developmental emergentism'. Philosophy of Science 65, 259-266. |
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McIntire, S.L., R.J. Reimer, K. Schuske, R.H. Edwards and E.M. Jorgensen. 1997. Identification and characterization of the vesicular GABA transporter. Nature 389, 870-876. |
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Nonet, M.L., J.E. Staunton, M. Kilgard, E. Hartwieg, T. Fergestad, H.R. Horvitz, E.M. Jorgensen, B.J. Meyer. 1997. C. elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles. J. Neurosci. 17: 8061-8073. |
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Jorgensen, E.M., Hartwieg, E., Yook, K., and Horvitz, H.R. 1996. Genetic screens for synaptic function mutants in the nematode C. elegans. In Basic Neuroscience in Invertebrates. Tenth Tokyo Metropolitan Institute for Neuroscience International Symposium. p. 217-226. |
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Jorgensen, E.M, E. Hartwieg, K. Schuske, M.L. Nonet, Y. Jin and H.R. Horvitz. 1995. Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans. Nature 378: 196-199. |
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Jorgensen, E.M. and M. Nonet. 1995. The C. elegans neuromuscular junction. Seminars in Developmental Biology 6, 207-220. |
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McIntire, S., E.M. Jorgensen, and H.R. Horvitz. 1993. Genes required for GABA function in the nematode Caenorhabditis elegans. Nature 364: 334-337. |
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McIntire, S., E.M. Jorgensen, J. Kaplan and H.R. Horvitz. 1993. The GABAergic nervous system of Caenorhabditis elegans. Nature 364: 337-341. |
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Riley, G.R., E.M. Jorgensen, R.K. Baker, and R. Garber. 1991. Positive and negative control of the Antennapedia promoter P2. Development Sup. 1: 177-185. |
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Jorgensen, E.M., and R. Garber. 1987. Function and misfunction of the two promoters of the Antennapedia gene in Drosophila. Genes and Development 1: 544-555. |
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Stroeher, V., E.M. Jorgensen, and R. Garber. 1986. Multiple transcripts from the Antennapedia gene of Drosophila melanogaster. Mol. Cell. Biol. 6: 4667-4675. |
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Book Chapters |
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Yook, K. and E.M. Jorgensen. 2000. Genetics of the Caenorhabditis elegans nervous system. In Encyclopedia of Genetics. Ed. S. Brenner, J. Miller, Academic Press, New York. pp. 1309-1314. |
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Jorgensen, E.M., and C. Rankin. 1997. Neural Plasticity. In:C. elegans II. Ed. D. Riddle, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. pp. 769-790. |
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