Baldomero M. Olivera's Publications

Olivera, B.M., P. Baine and N. Davidson (1964) Electrophoresis of the nucleic acids. Biopolymers 1:245-57. Davidson, N., J. Widholm, U.S. Nandi, R. Jensen, B.M. Olivera and J.C.Wang (1965) Preparation and properties of native crab dAT. Proc. Natl. Acad. Sci. USA 53:111-18. Olivera, B.M., R.C. Huang and N. Davidson (1965) Elektrophoretische Untersuchungen an Nukleoshistone. Ber. Bunsenges. Physik. Chem. 68:802-05. Schwimmer, S. and B.M. Olivera (1966) Electrophoretic properties of enzymically synthesized DNA. J. Mol. Biol. 20:585-87. Schwimmer, S. and B.M. Olivera (1966) Electrophoresis of products of DNA- and nucleohistone-supported DNA synthesis. Biopolymers 4:953-55. Ohlenbusch, H.H., B.M. Olivera, D. Tuan and N. Davidson (1967) Selective dissociation of histones from calf thymus nucleoprotein. J. Mol. Biol. 25:299-315. Olivera, B.M. and I.R. Lehman (1967) Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli. Proc. Natl. Acad. Sci. USA. 57:1426-33. Olivera, B.M. and I.R. Lehman (1967) Diphosphopyridine nucleotide: a cofactor for the polynucleotide joining enzyme from Escherichia coli. Proc. Natl. Acad. Sci. USA 57:1700-04. Wang, J.C., D. Baumgarten and B.M. Olivera (1967) On the origin of tertiary turns in covalently closed double-stranded cyclic DNA. Proc. Natl. Acad. Sci. USA 58:1852-58. Olivera, B.M. and I.R. Lehman (1968) Enzymatic joining of polynucleotides, III. The polydeoxyadenylate: polydeoxythymidylate homopolymer pair. J. Mol. Biol. 36:261-74. Olivera, B.M., I.E. Scheffler and I.R. Lehman (1968) Enzymatic joining of polynucleotides, IV. Formation of a circular deoxyadenylate: deoxythymidylate copolymer. J. Mol. Biol. 36:275-85. Olivera, B.M., Z. Hall and I.R. Lehman (1968) Enzymatic joining of polynucleotides, V. A DNA-adenylate intermediate in the polynucleotide-joining reaction. Proc. Natl. Acad. Sci. USA 61:237-44. Olivera, B.M., Z. Hall, Y. Anraku, J.R. Chien and I.R. Lehman (1968) On the mechanism of the polynucleotide joining reaction. Cold Spring Harbor Symp. Quant. Biol. 33:27-34. Laipis, P.J., B.M. Olivera and A.T. Ganesan (1969) Enzymatic cleavage and repair of transforming DNA. Proc. Natl. Acad. Sci. USA 62:289-96. Lundquist, R. and B.M. Olivera (1971) Pyridine nucleotide metabolism in Escherichia coli. I. Exponential growth. J. Biol. Chem. 246:1107-16. Olivera, B.M. and R. Lundquist (1971) DNA synthesis in Escherichia coli in the presence of cyanide. J. Mol. Biol. 57:263-77. Olivera, B.M. and F. Bonhoeffer (1972) Replication of fX174 DNA by Escherichia coli PolA- in vitro. Proc. Natl. Acad. Sci. USA 69:25-29. Olivera, B.M. and F. Bonhoeffer (1972) Discontinuous DNA replication in vitro. I. Two sizes of DNA intermediates. Nat. New Biol. 240:233-35. Olivera, B.M., K.G. Lark, R. Herrmann and F. Bonhoeffer (1972) Discontinuous DNA synthesis in vitro: A method for defining the role of factors in replication in DNA synthesis in vitro. R.D. Wells and R.B. Inman (eds.), University Park Press, Baltimore, 1973, pp. 215-31. Hillyard, D., M.C. Rechsteiner and B.M. Olivera (1973) Pyridine nucleotide metabolism in mammalian cells in culture. J. Cell Phys. 82:165-80. Lundquist, R. and B.M. Olivera (1973) Pyridine nucleotide metabolism in Escherichia coli. II. Niacin starvation. J. Biol. Chem. 248:5137-43. McLaren, J., D.T.C. Ngo and B.M. Olivera (1973) Pyridine nucleotide metabolism in Escherichia coli. III. Biosynthesis from alternative precursors in vivo. J. Biol. Chem. 248:5144-49. Manlapaz-Fernandez, P. and B.M. Olivera (1973) Pyridine nucleotide metabolism in Escherichia coli. IV. Turnover. J. Biol. Chem. 248:5150-5. Lundquist, R., P. Manlapaz-Fernandez and B.M. Olivera (1974) A specific effect of deoxycytidine 5'-triphosphate on DNA chain initiation in vitro. J. Mol. Biol. 83:541-43. Olivera, B.M. and F. Bonhoeffer (1974) Replication of Escherichia coli requires DNA polymerase I. Nature 250:513-14. Rechsteiner, M., K. Lund, D. Hillyard and B.M. Olivera (1974) Autoradiographic studies of pyridine nucleotide metabolism in human culture cells. J. Cell. Phys. 83:389-400. Cruz, L.J., A. Reyes, G. Corpuz, E.M. Tecson and B.M. Olivera (1975) A study of Conus venom proteins. NRCP Res. Bull. 31:122-42. Cruz, L.J., J.L. Salabao, E. Flores and B.M. Olivera (1975) Pyridine nucleotide metabolism: purification of a nicotinamide mononucleotide-specific deaminase. Kimika 1:40-63. Rechsteiner, M., D. Hillyard and B. Olivera (1975) Turnover of nicotinamide adenine dinucleotide in cultures of human cells. J. Cell Physiol. 88:207-18. Cruz, L.J., G. Corpuz and B.M. Olivera (1976) A preliminary study of Conus venom protein. The Veliger 18:302-08. Keyes, T.W., B.M. Olivera, D.J. Stewart and E.W. Hanly (1976) Pyridine nucleotide metabolism in imaginal discs of Drosophila melanogaster. Biochem. Gen. 14:197-207. Rechsteiner, M., D. Hillyard and B.M. Olivera (1976) Magnitude and significance of NAD turnover in human cell line D98/AH2. Nature 259:695-96. Rechsteiner, M., D. Hillyard and B.M. Olivera (1976) Turnover of NAD in cultures of human cells. J. Cell. Phys. 88:207-17. Cruz, L.J., G. Corpuz and B.M. Olivera (1978) Mating, spawning, development and feeding habits of Conus geographus in captivity. The Nautilus 92:150-03. Cruz, L.J., W.R. Gray and B.M. Olivera (1978) Purification and properties of a myotoxin from Conus geographus venom. Arch. Biochem. Biophys. 190:539-48. Thomas, K.R. and B.M. Olivera (1978) Processivity of DNA exonucleases. J. Biol. Chem. 253:424-29. Olivera, B.M. (1978) DNA intermediates at the E. coli replication fork: effect of dUTP. Proc. Nat. Acad. Sci. USA 75:238-42. Olivera, B.M., P. Manlapaz-Ramos, H.R. Warner and B.K. Duncan (1979) DNA intermediates at the E. coli replication fork. II. Studies on a mutant in uracil DNA glycosidase. J. Mol. Biol. 128:265-75. Thomas, K.R., P. Manlapaz-Ramos, R. Lundquist and B.M. Olivera (1979) Formation of Okazaki pieces at the E. coli replication fork in vitro. Cold Spring Harbor Symp. Quant. Biol. 43:231-37. Manser, T., B.M. Olivera and F.B. Haugli (1980) NAD turnover in microplasmodia of Physarum polycephalum. J. Cell Phys. 102:379-84. Olivera, B.M., M.C. Rechsteiner, P. Manlapaz-Ramos, L.J. Cruz and D. Hillyard (1980) ADP-ribosylation and the pyridine nucleotide cycle. In: Proceedings of the Conference of Novel ADP-Ribosylation of Regulatory Enzymes and Proteins, M. Smulson and T. Sugimura (eds.), Elsevier North Holland, pp. 85-98. Clark, C., B.M. Olivera and L.J. Cruz (1981) A toxin from Conus geographus venom which acts on the vertebrate central nervous system. Toxicon 19:691-99. Gray, W.R., A. Luque, B.M. Olivera, J. Barrett and L.J. Cruz (1981) Peptide toxins from Conus geographus venom. J. Biol. Chem. 256:4734-40. Hillyard, D., M. Rechsteiner, P.M. Ramos, J.S. Imperial, L.J. Cruz and B.M. Olivera (1981) The pyridine nucleotide cycle. Studies in E. coli and the human cell line D98/AH2. J. Biol. Chem. 256:8491-97. Ferro, A.M. and B.M. Olivera (1982) Poly (ADP-ribosylation) in vitro. Reaction parameters and enzyme mechanism. J. Biol. Chem. 257:7808-13. Liu, G.P., J. Foster, P. Manlapaz-Ramos and B.M. Olivera (1982) Nucleoside salvage pathway for NAD biosynthesis in Salmonella typhimurium. J. Bact. 152:1111-16. Lundquist, R.C. and B.M. Olivera (1982) Transient generation of displaced single-stranded DNA during nick translation. Cell 31:53-60. McIntosh, M., L.J. Cruz, M.W. Hunkapiller, W.R. Gray and B.M. Olivera (1982) Isolation and structure of a peptide toxin from the marine snail Conus magus. Arch. Biochem. Biophys. 218:329-34. Olivera, B.M. and A.M. Ferro (1982) Pyridine nucleotide metabolism and ADP-ribosylation. In: ADP-Ribosylation Reactions, O. Hayaishi and K. Ueda (eds.), Academic Press, New York, pp. 19-40. Ferro, A.M., N.P. Higgins and B.M. Olivera (1983) Poly(ADP-ribosylation) of a DNA topoisomerase. J. Biol. Chem. 258:6000-03. Gray, W.R., J.E. Rivier, R. Galyean, L.J. Cruz and B.M. Olivera (1983) Conotoxin MI: Disulfide bonding and conformational states. J. Biol. Chem. 258:12247-51. Higgins, N.P., P. Manlapaz-Ramos, R.T. Gandhi and B.M. Olivera (1983) Bacteriophage Mu: A transposing replicon. Cell 33:623-28. Higgins, N.P., D. Moncecchi, P. Manlapaz-Ramos and B.M. Olivera (1983) Mu DNA replication in vitro. J. Biol. Chem. 258:4293-97. Higgins, N.P., D. Moncecchi, M.M. Howe, P. Manlapaz-Ramos and B.M. Olivera (1983) Replicative transposition of bacteriophage Mu in vitro. In: Mechanisms of DNA Replication and Recombination, Alan R. Liss, New York, pp. 187-201. Hughes, K.T., B.T. Cookson, D. Ladika, B.M. Olivera and J.R. Roth (1983) 6-aminonicotinamide resistant mutants of Salmonella typhimurium. J. Bact. 154:1126-36. Hughes, K.T., D. Ladika, J.R. Roth and B.M. Olivera (1983) An indispensable gene for NAD biosynthesis in S. typhimurium. J. Bact. 155:213-21. Jimenez, E.C., B.M. Olivera and L.J. Cruz (1983) Localization of enzymes and possible toxin precusors in granules from Conus striatus venom. Toxicon Suppl. 3:199-202. Thomas, K.R. and B.M. Olivera (1983) Flexibility in RNA priming of Okazaki pieces at the E. coli replication fork. Nucleic Acids Res. 11:6531-39. Ferro, A.M., L.H. Thompson and B.M. Olivera (1984) Poly(ADP-ribosylation) and DNA topoisomerase I in different cell lines. In: Proteins Involved in DNA Replication, U. Hubscher and S. Spadari (eds.), Plenum Publishing Corp., pp. 441-47. Ferro, A.M., M.C. McElwain and B.M. Olivera (1984) Poly(ADP-ribosylation) of DNA topoisomerase I: A nuclear response to DNA-strand interruptions. Cold Spring Harbor Symp. Quant. Biol. 49:683-90. Ferro, A.M. and B.M. Olivera (1984) Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus. J. Biol. Chem. 259:547-54. Gray, W.R., F.A. Luque, R. Galyean, E. Atherton, R.C. Sheppard, B.L. Stone, A. Reyes, J. Alford, M. McIntosh, B.M. Olivera, L.J. Cruz and J. Rivier (1984) Conotoxin GI: Disulfide bridges, synthesis and preparation of iodinated derivatives. Biochemistry 23:2796-2802. Higgins, N.P. and B.M. Olivera (1984) Mu DNA replication in vitro: Criteria for initiation. Mol. Gen. Gene. 194:60-64. Higgins, N.P., P. Manlapaz-Ramos and B.M. Olivera (1984) Analysis of Mu DNA replicated on cellophane discs. In: Proteins Involved in DNA Replication, U. Hubscher and S. Spadari (eds.), Plenum Publishing Corp., pp. 63-67. Jeter, R.M., B.M. Olivera and J.R. Roth (1984) S. typhimurium synthesizes cobalamin (Vitamin B12) de novo under anaerobic growth conditions. J. Bact. 159:206-13. McIntosh, J.M., B.M. Olivera, L.J. Cruz and W.R. Gray (1984) g-Carboxyglutamate in a neuroactive toxin. J. Biol. Chem. 259:14343-46. Olivera, B.M., J.M. McIntosh, L.J. Cruz, F.A. Luque and W.R. Gray (1984) Purification and sequence of a presynaptic peptide toxin from C. geographus venom. Biochemistry 23:5087-90. Cruz, L.J., W.R. Gray, B.M. Olivera, R.D. Zeikus, L. Kerr, D. Yoshikami and E. Moczydlowski (1985) Conus geographus toxins that discriminate between neuronal and muscle sodium channels. J. Biol. Chem. 260:9280-88. Cruz, L.J., W.R. Gray, D. Yoshikami and B.M. Olivera (1985) Conus venoms: A rich source of neuroactive peptides. J. Toxicol.-Toxin Revs. 4:107-32. Gray, W.R., D.M. Middlemas, R. Zeikus, B.M. Olivera and L.J. Cruz (1985) Structure-activity relationships in a-conotoxins: a model. In: Peptides: Structure and Function, C.M. Deber, V.J. Hruby and K.D. Kopple (eds.), The Ninth American Peptide Symposium, Pierce Chemicals Pubs., pp. 823-32. Olivera, B.M., W.R. Gray, R. Zeikus, J.M. McIntosh, J. Varga, J. Rivier, V. de Santos and L.J. Cruz (1985) Peptide neurotoxins from fish-hunting cone snails. Science 230:1338-43. Olivera, B.M., J.M. McIntosh, C. Clark, D. Middlemas, W.R. Gray and L.J. Cruz (1985) A sleep-inducing peptide from C. geographus venom. Toxicon 23:277-82. Cruz, L.J. and B.M. Olivera (1986) Calcium channel antagonists. w-Conotoxin defines a new high affinity site. J. Biol. Chem. 261:6230-33. Ferro, A.M. and B.M. Olivera (1986) Intracellular pyridine nucleotide degradation and turnover. In: Coenzymes and Cofactors, D. Dolphin, R. Poulson and O. Avramovic (eds.), John Wiley and Sons, pp. 25-77. Moczydlowski, E., B.M. Olivera, W.R. Gray and G.R. Strichartz (1986) Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and m-conotoxins. Proc. Natl. Acad. Sci. USA 83:5321-25. Reynolds, I.J., J.A. Wagner, S.A. Snyder, S.M. Thayer, B.M. Olivera and R.J. Miller (1986) Brain voltage-sensitive calcium channel subtypes differentiated by w-conotoxin fraction GVIA. Proc. Nat. Acad. Sci. USA 83:8804-07. Cookson, B.T., B.M. Olivera and J.R. Roth (1987) Genetic characterization and regulation of the nadB locus of Salmonella typhimurium. J. Bact. 169:4285-93. Cruz, L.J., D.S. Johnson and B.M. Olivera (1987) Characterization of the w-conotoxin target. Evidence for tissue-specific heterogeneity in calcium channel types. Biochemistry 26:820-4. Cruz, L.J., G.W. LeCheminant and B.M. Olivera (1987) Biochemical studies of w-conotoxin GVIA, a peptide toxin inhibiting voltage sensitive Ca channels. In: Integration and Control of Metabolic Processes, O.L. Kon et al. (eds.), Cambridge University Press, pp. 95-102. Cruz, L.J., V. de Santos, G.C. Zafaralla, C.A. Ramilo, R. Zeikus, W.R. Gray and B.M. Olivera (1987) Invertebrate vasopressin/oxytocin homologs. Characterization of peptides from Conus geographus and Conus striatus venoms. J. Biol. Chem. 262:15821-24. Feldman, D.H., B.M. Olivera and D. Yoshikami (1987) Omega-Conus geographus toxin: a peptide that blocks calcium channels. FEBS Lett. 214:295-300. Hughes, K.T., B.M. Olivera and J.R. Roth (1987) Rec dependence of Mu transposition from P22-transduced fragments. J. Bact. 169:403-09. Jeter, R., J.C. Escalante-Semerena, D. Roof, B.M. Olivera and J. Roth (1987) Synthesis and use of Vitamin B12 in Escherichia coli and Salmonella typhimurium. In: Cellular and Molecular Biology, F.C. Neidhardt (ed.), ASM, Washington, D.C., pp. 6551-56. McCleskey, E.W., A.P. Fox, D. Feldman, L.J. Cruz, B.M. Olivera, R.W. Tsien and D. Yoshikami (1987) Calcium channel blockade by a peptide from Conus: Specificity and mechanism. Proc. Nat. Acad. Sci. USA 84:4327-31. Olivera, B.M., L.J. Cruz, V. de Santos, G. LeCheminant, D. Griffin, R. Zeikus, J.M. McIntosh, R. Galyean, J. Varga, W.R. Gray and J. Rivier (1987) Neuronal Ca channel antagonists. Discrimination between Ca channel subtypes using w-conotoxin from Conus magus venom. Biochemistry 26:2086-90. Rivier, J., R. Galyean, L. Simon, L.J. Cruz, B.M. Olivera and W.R. Gray (1987) Total synthesis and further characterization of the u-carboxyglutamate-containing "sleeper" peptide from Conus geographus venom. Biochemistry 26:8508-12. Rivier, J., R. Galyean, W.R. Gray, A. Azimi-Zonooz, J.M. McIntosh, L.J. Cruz and B.M. Olivera (1987) Neuronal calcium channel inhibitors. Synthesis of w-conotoxin GVIA and effects on 45Ca-uptake by synaptosomes. J. Biol. Chem. 262:1194-98. Wagner, J.A., A.M. Snowman, B.M. Olivera and S.H. Snyder (1987) Aminoglycoside effects on voltage-sensitive Ca channels and neurotoxicity. N. Engl. J. Med. 317:1669. DeAizpurua, H.J., E.H. Lambert, G.E. Griesmann, B.M. Olivera and J.A. Lennon (1988) Antagonism of voltage-gated calcium channels in small cell carcinomas of patients with and without Lambert-Eaton Myasthenic Syndrome by autoantibodies, w-conotoxin and adenosine. Cancer Res. 48:4719-24. Gray, W.R., B.M. Olivera, L.J. Cruz and J. Rivier (1988) A model for "sleeper peptide" (conotoxin GV) and other Gla-containing molecules. In: Peptide Chemistry 1987, T. Shiba and S. Sakakibara (eds.), Protein Research Foundation, Osaka, pp. 105-13. Gray, W.R., B.M. Olivera and L.J. Cruz (1988) Peptide toxins from venomous Conus snails. Ann. Rev. Biochem. 57:665-700. Hirning, L.D., A.P. Fox, E.W. McCleskey, B.M. Olivera, S.A. Thayer, R.J. Miller and R.W. Tsien (1988) Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 239:57-61. Hughes, K.T., B.M. Olivera and J.R. Roth (1988) Structural gene for NAD synthetase in Salmonella typhimurium. J. Bact. 120:2113-20. Kerr, L.M., F. Filloux, B.M. Olivera, H. Jackson and J.K. Walmsley (1988) Autoradiographic localization of calcium channels with [125I] w-conotoxin in rat brain. Eur. J. Pharmacol. 146:181-83. Olivera, B.M., W.R. Gray and L.J. Cruz (1988) Marine snail venoms. In: Handbook of Natural Toxins, Vol. 4, Marine Toxins and Venoms, A. Tu (ed.), Marcel Dekker, Inc., New York and Basel, pp. 327-52. Park, U.E., J.R. Roth and B.M. Olivera (1988) Salmonella typhimurium mutants lacking NAD pyrophosphatase. J. Bact. 170:3725-30. Wagner, J.A., A.M. Snowman, A. Biswas, B.M. Olivera and S.H. Snyder (1988) w-Conotoxin GVIA binding to a high-affinity receptor in brain: characterization, calcium sensitivity, and solubilization. J. Neurosci. 9:3354-59. Zafaralla, G.C., C. Ramilo, W.R. Gray, R. Karlstrom, B.M. Olivera and L.J. Cruz (1988) Phylogenetic specificity of cholinergic ligands: a-conotoxin SI. Biochemistry 27:7102-05. Zhu, N., B.M. Olivera and J.R. Roth (1988) Identification of a repressor gene involved in the regulation of NAD de novo biosynthesis in Salmonella typhimurium. J. Bact. 170:117-25. Wagner, J.A., S.E. Guggino, I.J. Reynolds, A.M. Snowman, A. Biswas, B.M. Olivera and S.H. Snyder (1988) Calcium antagonist receptors. Clinical and physiological relevance. Ann. N.Y. Acad. Sci. 552:116-33. Cruz, L.J., G. Kupryszewski, G.W. LeCheminant, W.R. Gray, B.M. Olivera and J. Rivier (1989) m-Conotoxin GIIIA, a peptide ligand for muscle sodium channels: chemical synthesis, radiolabeling and receptor characterization. Biochemistry 28:3437-42. Cruz, L.J. D.S. Johnson, J.S. Imperial, D. Griffin, G.W. LeCheminant, G.P. Miljanich and B.M. Olivera (1989) w-Conotoxins and voltage-sensitive calcium channel subtypes. Curr. Top. Memb. Transp. 33:417-29. Hillyard, D.R., B.M. Olivera, S. Woodward, G.P. Corpuz, W.R. Gray, C.A. Ramilo and L.J. Cruz (1989) A molluscivorous Conus toxin: conserved frameworks in conotoxins. Biochemistry 28:358-61. Olivera, B.M., K.T. Hughes, P. Cordray and J.R. Roth (1989) Aspects of NAD metabolism in prokaryotes and eukaryotes. In: ADP-Ribose Transfer Reactions. Mechanisms and Biological Significance, M.K. Jacobson and E.L. Jacobson (eds.), Springer Verlag, New York, pp. 353-60. Park, U.E., B.M. Olivera, K.T. Hughes, J.R. Roth and D.R. Hillyard (1989) DNA ligase and the pyridine nucleotide cycle in Salmonella typhimurium. J. Bact. 171:2173-80. Yoshikami, D., Z. Bagabaldo and B.M. Olivera (1989) The inhibitory effects of w-conotoxins on calcium channels and synapses. Ann. N.Y. Acad. Sci. 560:230-48. Zhu, N., B.M. Olivera and J.R. Roth (1989) Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium. J. Bact. 171:4402-09. Fox, A.P., L.D. Hirning, S. Kongsamut, E.W. McCleskey, R.J. Miller, B.M. Olivera, T.M. Perney, S.M. Thayer and R.W. Tsien (1990) The interaction of toxins with Ca channels. In: Neurotoxins and Their Pharmacological Implications, Raven Press. Haack, J.A., J. Rivier, T.N. Parks, E.E. Mena, L.J. Cruz and B.M. Olivera (1990) Conantokin-T. A l-carboxyglutamate containing peptide with N-methyl-D-aspartate antagonist activity. J. Biol. Chem. 265:6025-29. Hernandez, J.-F., B.M. Olivera, L.J. Cruz, R.A. Myers, J. Abbott and J. Rivier (1990) Synthesis, characterization and biological activity of conantokin-G. In: UCLA Symposia Conference on Biochemical and Biomedical Engineering Synthetic Peptides: Approaches to Biological Problems, Frisco, CO, February 22-March 4. Higgins, N.P., A.M. Ferro and B.M. Olivera (1990) DNA-topoisomerase modification. In: DNA Topology and its Biological Effects, N.R. Cozzarrelli and J.C. Wang (eds.), Cold Spring Harbor Laboratory Press., pp. 361-70. Mena, E.E., M.F. Gullak, M.J. Pagnozzi, K.E. Richter, J. Rivier, L.J. Cruz and B.M. Olivera (1990) Conantokin-G: A novel peptide antagonist to the N-methyl-D-aspartate (NMDA) receptor. Neurosci. Lett. 118:241-44. Myers, R.A., J.M. Mcintosh, J. Imperial, R.W. Williams, T. Oas, J.A. Haack, J.F. Hernandez, J. Rivier, L.J. Cruz and B.M. Olivera (1990) Peptides from Conus venoms which affect Ca++ entry into neurons. J. Toxin-Toxin Revs. 9:179-202. Olivera, B.M., D.R. Hillyard, J. Rivier, S. Woodward, W.R. Gray, G. Corpuz and L.J. Cruz (1990) Conotoxins: targeted peptide ligands from snail venoms. In: Marine Toxins: Origins, Structures and Molecular Pharmacology, S. Hall and G. Strichartz (eds.), American Chemical Society, Washington, D.C., pp. 256-78. Olivera, B.M., J. Rivier, C. Clark, C.A. Ramilo, G.P. Corpuz, F.C. Abogadie, E.E. Mena, S.R. Woodward, D.R. Hillyard and L.J. Cruz (1990) Diversity of Conus neuropeptides. Science 249:257-63. Woodward, S.R., L.J. Cruz, B.M. Olivera and D.R. Hillyard (1990) Constant and hypervariable regions in conotoxin propeptides. EMBO J. 1:1015-20. Hughes, K.T., J.R. Roth and B.M. Olivera (1991) A genetic characterization of the nadC gene of Salmonella typhimurium. Genetics 127:657-70. Myers, R.A., G.C. Zafaralla, W.R. Gray, J. Abbott, L.J. Cruz and B.M. Olivera (1991) a-Conotoxins, small peptide probes of the nicotinic acetylcholine receptor. Biochemistry 30:9370-7. Olivera, B.M., J.S. Imperial, L.J. Cruz, V.P. Bindokas, V.J. Venema and M.E. Adams (1991) Calcium channel-targeted polypeptide toxins. Ann. N.Y. Acad. Sci. 635:114-22. Olivera, B.M., J. Rivier, J.K. Scott, D.R. Hillyard and L.J. Cruz (1991) Conotoxins. J. Biol. Chem. 266:22067-70. Zhu, N., B.M. Olivera and J.R. Roth (1991) Activity of the nicotinamide mononucleotide transport system is regulated in Salmonella typhimurium. J. Bact. 173:1311-20. Lev-Ram, V., B.M. Olivera, I.B. Levitan, G.P. Corpus, C.A. Ramilo, D.R. Hillyard and L.J. Cruz (1991) Molluscan Conus venoms: a source of toxin probes for molluscan neurobiology. In: Molluscan Neurobiology (Proceedings of the third symposium on Molluscan Neurobiology, Amsterdam, Netherlands, August 20-24, 1990), K.S. Kits, H.H. Boer, J. Joosse (eds.), North-Holland, Amsterdam, pp. 328-34. Olivera, B.M., L.J. Cruz, R.A. Myers, D.R. Hillyard, J. Rivier and J.K. Scott (1992) Conus peptides and biotechnology. In: Neurotox '91: Molecular Basis of Drug and Pesticide Action, I.R. Duce (ed.), Elsevier, Applied Science, London, pp. 45-55. Olivera, B.M., D.S. Johnson, A. Azimi-Zoonooz and L.J. Cruz (1992) Peptides in the venom of the geography cone, Conus geographus. In: Toxins and Targets, D. Watters, M. Lavin, D. Maguire and J. Pearn (eds.), Harwood Academic Publishers, Chur, Switzerland, pp. 19-28. Hammerland, L.G., B.M. Olivera and D. Yoshikami (1992) Conantokin-G selectively inhibits NMDA-induced currents in Xenopus oocytes injected with mouse brain m-RNA. Eur. J. Pharmacol. 226:239-44. Cruz, L.J., C.A. Ramilo, G.P. Corpuz and B.M. Olivera (1992) Conus peptides: phylogenetic range of biological activity. Biol. Bull. 183:159-64. Hillyard, D.R., V.D. Monje, I.M. Mintz, B.P. Bean, L. Nadasdi, J. Ramachandran, G. Miljanich, A. Azimi-Zoonooz, J.M. McIntosh, L.J. Cruz, J.S. Imperial and B.M. Olivera (1992) A new Conus peptide ligand for mammalian presynaptic Ca channels. Neuron 9:69-77. Ramilo, C.A., G.C. Zafaralla, L. Nadasdi, L.G. Hammerland, D. Yoshikami, W.R. Gray, J. Ramachandran, G. Miljanich, B.M. Olivera and L.J. 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Barany, eds.), Kluwer Academic Publishers, Dordrecht, The Netherlands, 727-29. McIntosh, J.M., G.O. Corpuz, R.T. Layer, J.E. Garrett, J.D. Wagstaff, G. Bulaj, A. Vyazovkina, D. Yoshikami, L.J. Cruz and B.M. Olivera (2000) Isolation and characterization of a novel Conus peptide with apparent antinociceptive activity. J. Biol. Chem. 275:32391-97. Olivera, B.M. and L.J. Cruz (2001) Conotoxins, in retrospect. Toxicon 39:7-14. Jimenez, E.C., M. Watkins, L.J. Juszczak, L.J. Cruz and B.M. Olivera (2001) Contryphans from Conus textile venom ducts. Toxicon 39:803-08. Walker, C.S., R.P. Shetty, K. Clark, S.G. Kazuko, A. Letsou, B.M. Olivera and P.K. Bandyopadhyay (2001) On a potential global role for vitamin K-dependent g-carboxylation in animal systems. Evidence for a g-glutamyl carboxylase in Drosophila. J. Biol. Chem. 276:7769-74. Kulak, J.M., J.M. McIntosh, D. Yoshikami and B.M. Olivera (2001) Nicotine-evoked transmitter release in synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage-gated calcium channels. J. Neurochem. 77:2581-89. Jones, R.M., G.E. Cartier, J.M. McIntosh, G. Bulaj, V.E. Farrar and B.M. Olivera (2001) Composition and therapeutic utility of conotoxins from genus Conus. Patent status 1996-2000. .Exp Opin. Ther. Patents 11:603-23. Azimi-Zonooz, A., C.B. Kawa, C.D. Dowell and B.M. Olivera (2001) Autoradiographic localization of N-type VGCCs in gerbil hippocampus and failure of ω-conotoxin MVIIA to attenuate neuronal injury after transient cerebral ischemia. Brain Res. 907:61-70. Bulaj, G., R. DeLaCruz, A. Azimi-Zonooz, P. West, M. Watkins, D. Yoshikami and B.M. Olivera (2001) δ-Conotoxin structure/function through a cladistic analysis. Biochemistry 40:13201-08. Espiritu, D.J.D., M. Watkins, V. Dia-Monje, G.E. Cartier, L.J. Cruz and B.M. Olivera (2001) Venomous cone snails: molecular phylogeny and the generation of toxin diversity. Toxicon 39:1899-1916. Jones, R.M., G.E. Cartier, J.M. McIntosh, G. Bulaj, V.E. Farrar and B.M. Olivera (2001) Composition and therapeutic utility of conotoxins from genus Conus. Patent status 1996-2000. Exp. Opin. Ther. Patents 11:603-23. Bandyopadhyay, P.K., J.E. Garrett, R.P. Shetty, T. Keate, C.S. Walker and B.M. Olivera (2002) γ Glutamyl carboxylation: an extracellular post-translational modification that antedates the divergence of molluscs, arthropods and chordates. Proc. Natl. Acad. Sci. USA 99:1264-69. Maillo, M., M.B. Aguilar, E. Lopez-Vera, A.G. Craig, G. Bulaj, B.M. Olivera and E.P. Heimer de la Cortera (2002) Conorfamide, a Conus venom peptide belonging to the RFamide family of neuropeptides. Toxicon 40:401-17. Olivera, B.M. (2002) Conus venom peptides: reflections from the biology of clades and species. Annu. Rev. Ecol. Syst. 33:25-47. Olivera, B.M., J.S. Imperial and G. Bulaj (2002) Cone snails and conotoxins: evolving sophisticated neuropharmacology. In Perspectives in Molecular Toxinology (A. Menez, ed.), John Wiley and Sons Ltd, West Sussex, England, p. 143-58. Lirazan, M., E.C. Jimenez, A.G. Craig, B.M. Olivera and L.J. Cruz (2002) Conophysin-R, a Conus radiatus venom peptide belonging to the neurophysin family. Toxicon 40:901-08. Rong, Y.S., S. Titen, H. Xie, M.M. Golic, M. Bastiani, P. Bandyopadhyay, B.M. Olivera, M. Brodsky, G.M. Rubin and K.G. Golic (2002) Targeted mutagenesis by homologous recombination in Drosophila melanogaster. Genes Dev. 16:1568-81. Jimenez, E.C., S. Donevan, C. Walker, L.-M. Zhou, J. Nielsen, L.J. Cruz, H. Armstrong, H.S. White and B.M. Olivera (2002) Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency. Epilepsy Res. 51:73-80. McIntosh, J.M., C. Dowell, M. Watkins, J.E. Garrett, D. Yoshikami and B.M. Olivera (2002) α Conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors. J. Biol. Chem. 277:33610-15. West, P.J., G. Bulaj, J.E. Garrett, B.M. Olivera and D. Yoshikami (2002) μ-Conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons. Biochemistry 41:15388-93. Miles, L.A., C.Y. Dy, J. Nielsen, K.J. Barnham, M.G. Hinds, B.M. Olivera and G. Bulaj (2002) Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif. J. Biol. Chem. 277:43033-40. Espiritu, J.D., L.J. Cruz, G.E. Cartier and B.M. Olivera (2002) Venomous gastropods: Conus, conoideans and other neogastropod families. Bollettino Malacologico (Italy) Supplemento 4:147-60. Olivera, B.M. (2002) The gastropod genus Xenuroturris (Iredale, 1929) evaluated and a new turrid Lophiotoma olangoensis, described from the central Philippines. Sci. Diliman 14:39-49. Ferber, M., A. Sporning, G. Jeserich, R. DeLaCruz, M. Watkins, B.M. Olivera and H. Terlau (2003) A novel Conus peptide ligand for K+ channels. J. Biol. Chem. 278:2177-83. Ellison, M., J.M. McIntosh and B.M. Olivera (2003) α-Conotoxins ImI and ImII. Similar α7 nicotinic receptor antagonists act at different sites. J. Biol. Chem. 278:757-64. Van Wagoner, R.M., R.B. Jacobsen, B.M. Olivera and C.M. Ireland (2003) Characterization and three-dimensional structure determination of ψ-conotoxin PIIIF, a novel noncompetitive antagonist of nicotinic acetylcholine receptors. Biochemistry 42:6353-62. Jimenez, E.C., R.P. Shetty, M. Lirazan, J. Rivier, C. Walker, F.C. Abogadie, D. Yoshikami, L.J. Cruz and B.M. Olivera (2003) Novel excitatory Conus peptides define a new conotoxin superfamily. J. Neurochem. 85:610-21. Dowell, C., B.M. Olivera, J.E. Garrett, S.T. Saheli, M. Watkins, A. Kuryatov, D. Yoshikami, J.M. Lindstrom and J.M. McIntosh (2003) α-Conotoxin PIA is selective for α6 subunit-containing nicotinic acetylcholine receptors. J. Neurosci. 23:9445-52. Imperial, J.S., M. Watkins, P. Chen, D.R. Hillyard, L.J. Cruz and B.M. Olivera (2003) The augertoxins: biochemical characterization of venom components from the toxoglossate gastropod Terebra subulata. Toxicon 42:391-98. Chi, S.W., K.H. Park, J.E. Suk, B.M. Olivera, J.M. McIntosh and K.H. Han (2003) Solution structure of αA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus. J. Biol. Chem. 278:42208-13. Keizer, D.W., P.J. West, E.F. Lee, D. Yoshikami, B.M. Olivera, G. Bulaj and R.S. Norton (2003) Structural basis for tetrodotoxin-resistant sodium channel binding by μ-conotoxin SmIIIA. J. Biol. Chem. 278:46805-13. Bulaj, G., O. Buzek, I. Goodsell, E.C. Jimenez, J. Kranshi, J.S. Nielsen, J.E. Garrett and B.M. Olivera (2003) Efficient oxidative folding of conotoxins and the radiation of venomous cone snails. Proc. Natl. Acad. Sci. USA 100 (suppl 2):14562-68. Koch, E.D., B.M. Olivera, H. Terlau and F. Conti (2004) The binding of κ-conotoxin PVIIA and fast C-type inactivation of Shaker K+ channels are mutually exclusive. Biophys. J. 86:191-209. Santos A.D., J.M. McIntosh, D.R. Hillyard, L.J. Cruz and B.M. Olivera (2004) The A-superfamily of conotoxins: structural and functional divergence. J. Biol. Chem. 2003 Dec 30 [Epub ahead of print] Terlau, H. and B.M. Olivera (2004) Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol. Rev. 83: in press. Aguilar, M.B., E. López-Vera, J.S. Imperial, A. Falcón, B.M. Olivera and E.P. Heimer de la Cotera (2005) Putative γ-conotoxins in vermivorous cone snails: the case of Conus delessertii. Peptides 26:23-27. Braga, M.C.V., K. Konno, F.C.V. Portaro, J. Carlos de Freitas, T. Yamane, B.M. Olivera and D.C. Pimenta (2005) Mass spectrometric and high performance liquid chromatography profiling of the venom of the Brazilian vermivorous mollusk Conus regius: feeding behavior and identification of one novel conotoxin. Toxicon 45:113-22. Buczek, O., D. Yoshikami, G. Bulaj, E.C. Jimenez and B.M. Olivera (2005) Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide. J. Biol. Chem. 280:4247-53. Garrett, J.E., O. Buczek, M. Watkins, B.M. Olivera and G. Bulaj (2005) Biochemical and gene expression analyses of conotoxins in Conus textile venom ducts. Biochem. Biophys. Res. Comm. 328(1):362-67. Teichert, R.W., J. Rivier, J. Torres, J. Dykert, C. Miller and B.M. Olivera (2005) A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor. J. Neurosci. 25:732-36. Teichert, R. W., Jimenez, E. C., and Olivera, B. M. (2005). α S-conotoxin RVIIIA: a structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors. Biochemistry 44, 7897-902. Verdier, L., Al-Sabi, A., Rivier, J. E., Olivera, B. M., Terlau, H. & Carlomagno, T. (2005) Identification of a novel pharmacophore for peptide toxins interacting with K+ channels. J Biol Chem, 280, 21246-55. Bandyopadhyay, P. K., Clark, K., Stevenson, B. J., Rivier, J. E., Olivera, B. M., Golic, K. G., and Rong, Y. S. (2006). Biochemical characterization of Drosophila γ-glutamyl carboxylase and its role in fly development. Insect Mol Biol 15, 147-56. Bandyopadhyay, P. K., Stevenson, B. J., Cady, M. T., Olivera, B. M., and Wolstenholme, D. R. (2006). Complete mitochondrial DNA sequence of a Conoidean gastropod, Lophiotoma (Xenuroturris) cerithiformis: gene order and gastropod phylogeny. Toxicon 48, 29-43. Bulaj, G., Zhang, M. M., Green, B. R., Fiedler, B., Layer, R. T., Wei, S., Nielsen, J. S., Low, S. J., Klein, B. D., Wagstaff, J. D., Chicoine, L., Harty, T. P., Terlau, H., Yoshikami, D., and Olivera, B. M. (2006). Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity. Biochemistry 45, 7404-14. Ellison, M., Haberlandt, C., Gomez-Casati, M. E., Watkins, M., Elgoyhen, A. B., Mcintosh, J. M. & Olivera, B. M. (2006) α-RgIA: a novel conotoxin that specifically and potently blocks the α9α10 nAChR. Biochemistry, 45, 1511-7. Imperial, J. S., Bansal, P. S., Alewood, P. F., Daly, N. L., Craik, D. J., Sporning, A., Terlau, H., Lopez-Vera, E., Bandyopadhyay, P. K., and Olivera, B. M. (2006). A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry 45, 8331-40. Olivera, B. M. (2006). Conus peptides: biodiversity-based discovery and exogenomics. J Biol Chem 281, 31173-7. Teichert, R. W., Lopez-Vera, E., Gulyas, J., Watkins, M., Rivier, J., and Olivera, B. M. (2006). Definition and characterization of the short αA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry 45, 1304-12. Vincler, M., Wittenauer, S., Parker, R., Ellison, M., Olivera, B. M. & Mcintosh, J. M. (2006) Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A, 103, 17880-4. Watkins, M., Hillyard, D. R., and Olivera, B. M. (2006). Genes expressed in a turrid venom duct: divergence and similarity to conotoxins. J Mol Evol 62, 247-56. Zhang, M. M., Fiedler, B., Green, B. R., Catlin, P., Watkins, M., Garrett, J. E., Smith, B. J., Yoshikami, D., Olivera, B. M., and Bulaj, G. (2006). Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels. Biochemistry 45, 3723-32. Zugasti-Cruz, A., Maillo, M., Lopez-Vera, E., Falcon, A., Heimer De La Cotera, E. P., Olivera, B. M. & Aguilar, M. B. (2006) Amino acid sequence and biological activity of a γ-conotoxin-like peptide from the worm-hunting snail Conus austini. Peptides, 27, 506-11. Bandyopadhyay, P.K., Stevenson, B.J., Ownby, J.P., Cady, M.T., Watkins, M., Olivera, B.M. (2007) The Mitochondrial Genome of Conus textile, coxI-coxII Intergenic Sequences and Conoidean Evolution. Molecular Phylogenetics and Evolution. 46 215-223. Biggs, J., Rosenfeld, Y., Shai, Y., and Olivera, B. M. (2007) Conolysin-Mt: A Conus Peptide that Disrupts Cellular Membranes. Biochemistry, Submitted. Buczek, O., Jimenez, E. C., Yoshikami, D., Imperial, J. S., Watkins, M., Morrison, A., and Olivera, B. M. (2007) I1-Superfamily Conotoxins and Prediction of Single D-Amino-Acid Occurence. Toxicon. Submitted. Buczek, O., Wei, D., Babon, J. J., Yang, X., Fiedler, B., Yoshikami, D., Olivera, B. M., Bulaj, G., and Norton, R. S. (2007) Structure and Sodium Channel Activity of an Excitatory I1-Superfamily Conotoxin. Biochemistry, 46, 9929-9940. Buczek, O., Green, B. R. & Bulaj, G. (2007) Albumin is a redox-active crowding agent that promotes oxidative folding of cysteine-rich peptides. Biopolymers, 88, 8-19. Ellison, M. & Olivera, B. M. (2007) α4/3 Conotoxins: Phylogenetic Distribution, Functional Properties and Structure-Function. The Chemical Record, 7, 341-353. Green, B. R., Catlin, P., Zhang, M. M., Fiedler, B., Bayudan, W., Morrison, A., Norton, R. S., Smith, B. J., Yoshikami, D., Olivera, B. M., and Bulaj, G. (2007) Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity. Chem Biol 14, 399-407. Heralde III, F. M., M. Watkins, J.-P. Ownby, P. Bandyopadhyay, A. D. Santos, G. P. Concepcion, and B. M. Olivera. 2007. Molecular Phylogeny of Some Indo-Pacific Genera in the Subfamily Turrinae H. Adams and A. Adams, 1853 (1838). Nautilus. , Pp. Imperial, J., Kantor, Y., Watkins, M., Heralde, F., Stevenson, B. J., Chen, P., Ownby, J.-P., Bouchet, P., and Olivera, B. M. (2007) The Venomous Auger Snail Hastula (impages) hecitca (Linnaeus, 1758): Molecular Phylogeny, Foregut Anatomy and Comparative Toxinology. Journal of Experimental Zoology, Part B, 6,744-756. Imperial, J. S., Silverton, N., Olivera, B. M., Bandyopadhyay, P. K., Sporning, A., Ferber, M., and Terlau, H. (2007) Using Chemistry to Reconstruct Evolution: On the Origins of Fish-hunting in Venomous Cone Snails. Proc American Philosophical Society, 151, 185-200. Jimenez, E. C., B. M. Olivera, and R. W. Teichert. 2007. αC-Conotoxin PrXA: A New Family of Nicotinic Acetylcholine Receptor Antagonists. Biochemistry, 46(30); 8717-8724. Leipold, E., De Bie, H., Zorn, S., Borges, A., Olivera, B. M., Terlau, H. & Heinemann, S. H. (2007) μO-Conotoxins Prevent Nav Channels from Opening by Interacting with the Voltage Sensor in Domain-2. Channels, Published. Lopez-Vera, E., Jacobsen, R. B., Ellison, M., Olivera, B. M., and Teichert, R. W. (2007) A novel α conotoxin (α-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors. Toxicon. 49(8):1193-9 Luna-Ramirez, K. S., Aguilar, M. B., Falcon, A., Heimer de la Cotera, E. P., Olivera, B. M., and Maillo, M. (2007) An O-conotoxin from the vermivorous Conus spurius active on mice and mollusks. Peptides 28, 24-30. Olivera, B.M., and Teichert, R.W. (2007) Diversity of the Neurotoxic Conus Peptides. Molecular Interventions 7(5): 251-260. Teichert, R. W., Jacobsen, R., Terlau, H., Yoshikami, D., and Olivera, B. M. (2007). Discovery and characterization of the short κA-conotoxins: a novel subfamily of excitatory conotoxins. Toxicon 49, 318-28. Teichert, R. W. & Olivera, B. M. (2007) Biology and Pharmacology of Conotoxins. IN JANKOVIC, J. (Ed.) Botulinum and other Neurotoxins: Translating Science Into Therapeutic Applications. New York, NY, Neurotoxin Institute. Teichert, R. W. & Olivera, B. M. (2007) Novel Pain Therapies from Marine Toxins. IN WALSH, P. A., SMITH, S. L., FLEMING, L. E., SOLO-GABRIELE, H. & GERWICK, W. H. (Eds.) Oceans and Human Health: Risks and Remedies from the Seas. San Diego, CA, Academic Press. Teichert, R.W., Jimenez, E.C., Twede, V., Watkins, M., Hollmann, M., Bulaj, G., Olivera, B.M. (2007) Novel Conantokins from Conus parius Venom are Specific Antagonists of N-Methyl-D-aspartate Receptors. JBC, 282: 36905-36913. Whiteaker, P., Christensen, S., Yoshikami, D., Dowell, C., Watkins, M., Gulyas, J., Rivier, J., Olivera, B. M., and McIntosh, J. M. (2007) Discovery, Synthesis, and Structure Activity of a Highly Selective α7 Nicotinic Acetylcholine Receptor Antagonist. Biochemistry. 46(22):6628-38 Zhang, M. M., Green, B. R., Catlin, P., Fiedler, B., Azam, L., Chadwick, A., Terlau, H., McArthur, J. R., French, R. J., Gulyas, J., Rivier, J. E., Smith, B. J., Norton, R. S., Olivera, B. M., Yoshikami, D., and Bulaj, G. (2007) Structure/Function Characterization of μ-Conotoxin KIIIA, An Irreversible Blocker of a Neuronal Subtype of Mammalian Sodium Channel. J Biol Chem, 282: 30699 - 30706. Bulaj, G., and Olivera, B. M. (2008) Folding of Conotoxins: Formation of the Native Disulfide Bridges during Chemical Synthesis and Biosynthesis of Conus Peptides. Antioxidant and Redox Signaling (ARS) , 10,141-155. Holford, M., Zhang, M. M., Catlin, P., Azam, L., Fiedler, B., Green, B. R., Watkins, M., Ownby, J.-P., Yoshikami, D., Bulaj, G., and Olivera, B. M. (2008) Discovery of a Nav1.7 Sodium Channel-Blocking Conotoxin from Conus bullatus. FASEBJ, Submitted. Lluisma, A. O., Lopez-Vera, E., Bulaj, G., Watkins, M., and Olivera, B. M. (2008) Characterization of a novel ψ -conotoxin from Conus parius Reeve. Toxicon, 51 (2), 174-180. Olivera, B. M., and Biggs, J. (2008) Living Species of the Genus Turridrupa Hedley, 1922, Found in the Philippines. Zootaxa, Submitted. Teichert, R., Garcia, C., Potian, J., Schmidt, J., Witzemann, V., Olivera, B.M., and McArdle, J. (2008) Peptide-Toxin Tools for Probing the Expression and Function of Fetal and Adult Subtypes of the Nicotinic Acetylcholine Receptor. Annals of the New York Academy of Sciences, In Press. Fielder, B., Zhang, M. M., Buczek, O., Azam, L., Bulaj, G., Norton, R., Olivera, B. M., Yoshikami, D. (2008) Specificity, Affinity, and Efficacy of ιa-Conotoxin RXIA, and Agonist of Voltage-Gated Sodium Channels Nav1.2, 1.6 and 1.7. Biochemical Pharmacology, 75: 2334-2344. Russell W. Teichert, Elsie C. Jiminez and Baldomero M. Olivera. (2008) Biology and Pharmacology of Conotoxins.

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